Figure 5

Functional enviromics map obtained from the full envirome data set. The regression coefficients of the PLP inner model were used to compute the effect of each environmental variable on the incremental variance in extracellular fluxes explained by each EM (columns in the colormap and vertical bars; see Figure 1 and Methods for calculation methods). Thus, they establish a statistical correlation between core cellular functions intensity and environmental factors, which can be exploited for the design of enhanced medium formulations and/or bioprocess operations.