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Table 1 Proteins identified as members of the "central core of cervical cancer".

From: Proteomic patterns of cervical cancer cell lines, a network perspective

Accession number Name Score Expect Searched-Matched Coverage
GRP78_HUMAN 78 kDa glucose-regulated protein 391 1.60E-035 91 - 46 58%
ENOA_HUMAN Alpha-enolase 327 4.00E-029 82 - 34 82%
GRP78_HUMAN 79 kDa glucose-regulated protein 302 1.30E-026 64 - 32 47%
HSP7C_HUMAN Heat shock cognate 71 kDa protein 294 8.10E-026 70 - 39 48%
VIME_HUMAN Vimentin 290 2.00E-025 64 - 33 63%
ENOA_HUMAN Alpha-enolase 286 5.10E-025 82 - 34 82%
PDIA1_HUMAN Protein disulfide-isomerase 252 1.30E-021 77 - 30 55%
ANXA2_HUMAN Annexin A2 249 2.60E-021 65 - 31 72%
TBB5_HUMAN Tubulin beta chain 247 4.00E-021 73 - 32 62%
ANXA4_HUMAN Annexin A4 233 1.00E-019 50 - 25 59%
EFTU_HUMAN Elongation factor Tu, mitochondrial 217 4.00E-018 44 - 22 52%
TPIS_HUMAN Triosephosphate isomerase 206 5.10E-017 42 - 17 69%
VIME_HUMAN Vimentin 206 5.10E-017 62 - 23 50%
PGAM1_HUMAN Phosphoglycerate mutase 1 205 2.10E-016 41 - 18 58%
ATPB_HUMAN ATP synthase subunit beta, mitochondrial 193 1.00E-015 84 - 44 72%
ACTG_HUMAN Actin, cytoplasmic 2 192 1.30E-014 50 - 20 48%
PUR9_HUMAN Bifunctional purine biosynthesis protein PURH 191 1.60E-015 49 - 22 45%
KCRB_HUMAN Creatine kinase B-type 178 3.20E-014 50 - 19 48%
EF2_HUMAN Elongation factor 2 154 8.10E-012 67 - 26 33%
HYOU1_HUMAN Hypoxia up-regulated protein 1 154 8.10E-012 38 - 19 22%
KCRB_HUMAN Creatine kinase B-type 154 8.10E-012 50 - 19 48%
PPIA_HUMAN Peptidyl-prolyl cis-trans isomerase A 150 2.00E-011 45 - 16 81%
GELS_HUMAN Gelsolin 147 4.00E-011 46 - 19 30%
VINC_HUMAN Vinculin 145 6.40E-011 36-19 20%
WDR1_HUMAN WD repeat-containing protein 1 144 8.10E-011 46 - 16 31%
EZRI_HUMAN Ezrin 131 1.60E-009 60 - 26 34%
HSP71_HUMAN Heat shock 70 kDa protein 1A/1B 129 2.60E-009 42 - 21 33%
TBA1C_HUMAN Tubulin alpha-1C chain 127 4.00E-009 45 - 13 37%
PRDX1_HUMAN Peroxiredoxin-1 126 5.10E-009 53 - 18 58%
PDIA3_HUMAN Protein disulfide-isomerase A3 125 6.40E-009 47 - 15 28%
GRP75_HUMAN Stress-70 protein, mitochondrial 123 1.00E-008 81 - 34 43%
DHSA_HUMAN Succinate dehydrogenase flavoprotein subunit 122 3.30E-007 39 - 17 21%
RSSA_HUMAN 40S ribosomal protein SA 121 1.60E-008 37 - 11 34%
HS90B_HUMAN Heat shock protein HSP 90-beta 119 2.6e-08 44 - 19 27%
ESTD_HUMAN S-formylglutathione hydrolase 114 8.10E-008 25 - 11 41%
TKT_HUMAN Transketolase 114 8.10E-008 52 - 19 32%
LDHB_HUMAN L-lactate dehydrogenase B chain 112 1.30E-007 43 - 20 36%
AL1A1_HUMAN Retinal dehydrogenase 1 110 2.00E-007 58 - 19 34%
IPYR_HUMAN Inorganic pyrophosphatase 110 2.00E-007 22 - 9 35%
DDX3X_HUMAN ATP-dependent RNA helicase DDX3X 108 3.20E-007 23 - 13 20%
DHE3_HUMAN Glutamate dehydrogenase 1, mitochondrial 107 4.00E-007 38 - 13 29%
G3P_HUMAN Glyceraldehyde-3-phosphate dehydrogenase 107 4.00E-007 55 - 13 42%
ACON_HUMAN Aconitate hydratase, mitochondrial 105 6.40E-007 54 - 23 30%
ML12A_HUMAN Myosin regulatory light chain 12A 105 6.40E-007 32 - 11 63%
RIR1_HUMAN Ribonucleoside-diphosphate reductase large subunit 101 1.60E-006 28 - 15 18%
EF2_HUMAN Elongation factor 2 99 2.60E-006 60-20 29%
QCR1_HUMAN Cytochrome b-c1 complex subunit 1, mitochondrial 98 3.30E-006 45 - 15 29%
CNN2_HUMAN Calponin-2 96 4.50E-006 51 - 13 48%
PCBP1_HUMAN Poly(rC)-binding protein 1 94 8.30E-006 39 - 14 44%
IMMT_HUMAN Mitochondrial inner membrane protein 92 1.30E-005 34 - 13 20%
CAPG_HUMAN Macrophage capping protein 91 1.80E-005 41 - 11 30%
TCTP_HUMAN Translationally-controlled tumor protein 91 1.80E-005 19 - 8 40%
PSB4_HUMAN Proteasome subunit beta type-4 89 1.70E-003 20 - 7 34%
TERA_HUMAN Transitional endoplasmic reticulum ATPase 88 3.10E-005 49 - 15 21%
K2C1_HUMAN Keratin, type II cytoskeletal 1 87 3.70E-005 46 - 13 29%
LEG1_HUMAN Galectin-1 84 7.70E-005 41 - 8 51%
1433Z_HUMAN 14-3-3 protein zeta/delta 80 2.30E-004 43 - 14 54%
LMNA_HUMAN Prelamin-A/C 78 3.40E-004 37 - 11 22%
HNRPL_HUMAN Heterogeneous nuclear ribonucleoprotein L 77 4.10E-004 27 - 13 16%
TCPH_HUMAN T-complex protein 1 subunit eta 77 4.00E-004 36 - 15 30%
OSBL8_HUMAN Oxysterol-binding protein-related protein 8 73 1.10E-003 56 - 13 21%
TCPE_HUMAN T-complex protein 1 subunit epsilon 71 1.70E-003 30 - 11 23%
HYOU1_HUMAN Hypoxia up-regulated protein 1 70 2.20E-003 28 - 13 14%
PSA5_HUMAN Proteasome subunit alpha type-5 69 2.70E-003 17 - 6 25%
FOXP3_HUMAN Forkhead box protein P3 68 3.40E-003 41 - 12 34%
  1. The entry name corresponds to the UniProt database, the score and expect value were obtained from the search engine Mascot. The expect value is the number of matches with equal or better scores that are expected to occur by chance alone. Score as -10*LOG10(P), where P is the absolute probability. The lower the expectation value, the more significant the score.