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Figure 4 | BMC Systems Biology

Figure 4

From: Integrative network analysis reveals active microRNAs and their functions in gastric cancer

Figure 4

Over-expressed miR-148a reduces cells growth. Cell growth was monitored in real-time using the xCELLigence system. (A, B) AGS and (C, D) SC-M1 tumor cells were transfected with either miR-148a precursor or inhibitor and compared to their respective negative controls. The results indicated that miR-148a reduced tumor cell growth (t-test, P = 0.23, A and P < 0.001, C), while miR-148a inhibitor-transfected tumor cells showed increased cell growth (t-test, P < 0.001, B and P < 0.001, D). Black and gray solid lines represent miR-148a precursor and inhibitor, respectively. Dashed lines represent their negative controls. The p-value was calculated using a paired t-test.

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