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Table 1 NIMS ranks against four types of background networks

From: Network target for screening synergistic drug combinations with application to traditional Chinese medicine

   Rank among 62 agent pairs #
Given agent Partner agent Angiogenesis network (NIMS score) PPI KNC MNC
5-fluorouracil Vinblastine* 2 (0.18104) 1 2 2
  Rapamycin* 3 (0.13744) 2 3 26
Vinblastine Camptothecin* 1 (0.19927) 1 1 3
Genistein Camptothecin* 2 (0.12070) 3 2 2
  Rapamycin* 6 (0.11533) 4 7 4
Sinomenine Matrine 4 (0.10923) 6 3 11
  Honokiol 8 (0.10142) 5 9 16
  Luteolin 10 (0.10007) 11 17 6
  Quercetin 14 (0.09835) 20 5 3
  Paeoniflorin 29 (0.08215) 26 29 31
  1. *: Agent pairs with known synergistic effects.
  2. #: For each given agent, there are totally 62 candidate agent pairs. PPI, protein-protein interaction network. KNC, Keep Node Content pathway network. MNC, Merge Node Content pathway network.