BMC Systems Biology

Table 2 Part of the results of double parameter perturbation analysis

From: An improved kinetic model for the acetone-butanol-ethanol pathway of Clostridium acetobutylicum and model-based perturbation analysis

P1+5%, P2+5%					P1-5%, P2-5%
P1	Enz1	P2	Enz2	Rd	P1	Enz1	P2	Enz2	Rd
Vmax14	B-C-B	Vmax19	BDH	0.0153	Vmax14	B-C-B	Vmax19	BDH	-0.0163
Vmax14	B-C-B	Vmax17	BK	0.0138	Vmax14	B-C-B	Vmax17	BK	-0.0145
Vmax15	CoAT	Vmax17	BK	-0.001	Vmax15	CoAT	Vmax17	BK	0.001
Vmax17	BK	Vmax19	BDH	0.0137	Vmax17	BK	Vmax19	BDH	-0.0146
Vmax18	PTB	Vmax19	BDH	0.0016	Vmax18	PTB	Vmax19	BDH	-0.0018
Vmax7	AK	Vmax8	CoAT	0.0053	Vmax7	AK	Vmax8	CoAT	-0.0053
Vmax9	PTA	Vmax11	AAD	-0.0014	Vmax9	PTA	Vmax11	AAD	0.0014
Vmax1	PTS	Vmax14	B-C-B	0.0163	Vmax1	PTS	Vmax14	B-C-B	-0.0171
Vmax1	PTS	Vmax19	BDH	0.0163	Vmax1	PTS	Vmax19	BDH	-0.0172
P1+5%, P2-5%					P1-5%, P2+5%
P1	Enz1	P2	Enz2	Rd	P1	Enz1	P2	Enz2	Rd
Vmax14	B-C-B	Vmax19	BDH	-0.0007	Vmax14	B-C-B	Vmax19	BDH	-0.0007
Vmax14	B-C-B	Vmax17	BK	0.0012	Vmax14	B-C-B	Vmax17	BK	-0.002
Vmax15	CoAT	Vmax17	BK	-0.0135	Vmax15	CoAT	Vmax17	BK	0.0136
Vmax17	BK	Vmax19	BDH	-0.0021	Vmax17	BK	Vmax19	BDH	0.0012
Vmax18	PTB	Vmax19	BDH	-0.0143	Vmax18	PTB	Vmax19	BDH	0.0138
Vmax7	AK	Vmax8	CoAT	0.0057	Vmax7	AK	Vmax8	CoAT	-0.0056
Vmax9	PTA	Vmax11	AAD	-0.0009	Vmax9	PTA	Vmax11	AAD	0.0009
Vmax1	PTS	Vmax14	B-C-B	0.0008	Vmax1	PTS	Vmax14	B-C-B	-0.0012
Vmax1	PTS	Vmax19	BDH	0.0008	Vmax1	PTS	Vmax19	BDH	-0.0011

This table lists part of the results of perturbation tests on double parameter pairs. Here “P1” and “P2” denote the parameters perturbed. “Enz1” and “Enz2” denote the corresponding enzymes. “+/- 5%” and “B-C-B” stand for the same meaning as in Table 1.

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