Table 1 Identified active regulatory networks in three stages in GK and WKY rats individually. The thresholds of significant pathways in different stages are set to be 0.05.
From: Network screening of Goto-Kakizaki rat liver microarray data during diabetic progression
| Â | GK | WKY |
|---|---|---|
4 w | HSC_LATEPROGENITORS_ADULT | HASLINGER_B_CLL_MUTATED NGUYEN_KERATO_UP P21_P53_MIDDLE_DN UVB_NHEK1_C2 VEGFPATHWAY VEGF_HUVEC_30MIN_UP YAGI_AML_PROG_ASSOC ZHAN_MM_CD138_CD1_VS_REST |
8-12 w | ATRIA_UP GLYCEROPHOSPHOLIPID_METABOLISM GOLUB_ALL_VS_AML_UP HOHENKIRK_MONOCYTE_DEND_UP HSC_LATEPROGENITORS_ADULT INTEGRINPATHWAY INTEGRIN_MEDIATED_CELL_ADHESION_KEGG LINDSTEDT_DEND_8H_VS_48H_DN LONGEVITYPATHWAY MEF2DPATHWAY P35ALZHEIMERSPATHWAY RCC_NL_UP VHL_NORMAL_UP | ALKPATHWAY BRENTANI_PROTEIN_MODIFICATION CELL_DEATH HCC_SURVIVAL_GOOD_VS_POOR_UP HSC_LATEPROGENITORS_SHARED ICF_UP NI2_LUNG_DN PARK_RARALPHA_MOD SCHURINGA_STAT5A_UP TGFBPATHWAY |
16-20 w | ASTON_OLIGODENDROGLIA_MYELINATION_SUBSET BRCA_BRCA1_NEG LEI_HOXC8_DN TESTIS_EXPRESSED_GENES TSADAC_RKOEXP_UP VEGFPATHWAY | NUCLEAR_RECEPTORS |