Gene expression signature (A) Heat map of 2,502 genes in the hiPSCs and parental cells. Cell types are indicated by colored bars. (B) Heat maps for the MRC, AM, UtE, and PAE hiPSCs and their corresponding parental cells. The hiPSCs and the parental SCs are discriminated by colored bars (red, SCs; purple, hiPSCs). (C) GO terms in the Biological Process, with the significance probabilities for the genes with higher and lower levels of expression. GO terms were summarized into 33 terms, as a macroscopic view, and the overlapped terms in the higher and lower expression classes are indicated by bold characters. See also additional file 6.