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Table 1 Relationships between glycosyltransferase expression, network, and glycan signature

From: Possible linkages between the inner and outer cellular states of human induced pluripotent stem cells

Glycosyltransferase Functions Glycan structure
ST6GAL1 N-, O-Glycan and glycolipid biosynthesis Siaa2,6Galb1,4GlcNAc-R
B3GNT3 O-Glycan biosynthesis core1 extension
GCNT2 N-, O-Glycan and glycolipid biosynthesis I antigen Siaa2,3Galb1,3GalNAca1-
ST3GAL1 O-Glycan biosynthesis Ser/Thr
FUT2 N-, O-Glycan and glycolipid biosynthesis H antigen
GALNT6 O-Glycan biosynthesis GalNAca1-Ser/Thr
GALNT8 O-Glycan biosynthesis GalNAca1-Ser/Thr
GALNT10 O-Glycan biosynthesis GalNAca1-Ser/Thr
GALNT12 O-Glycan biosynthesis GalNAca1-Ser/Thr
GALNT14 O-Glycan biosynthesis GalNAca1-Ser/Thr
GALNTL2 Unknown  
B3GALT5 N-, O-Glycan and glycolipid biosynthesis Galb1,3GlcNAc-R, SSEA-3
B3GALT1 N-, O-Glycan and glycolipid biosynthesis N- and O-Glycan, keratan sulfate Galb1,3GlcNAc-R
B3GNT2 biosynthesis polylactosamine
  1. The fourteen glycosyltransferases with identified correspondences between expression, network, and glycan signatures were allocated to biosynthetic pathways, using the KEGG GLYCAN database with modifications. The names of the pathways are listed. See also additional file 12 for the detailed pathways of notable glycosyltransferases, according to the KEGG GLYCAN database.
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BMC Systems Biology

ISSN: 1752-0509

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