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Table 1 Relationships between glycosyltransferase expression, network, and glycan signature

From: Possible linkages between the inner and outer cellular states of human induced pluripotent stem cells

Glycosyltransferase

Functions

Glycan structure

ST6GAL1

N-, O-Glycan and glycolipid biosynthesis

Siaa2,6Galb1,4GlcNAc-R

B3GNT3

O-Glycan biosynthesis

core1 extension

GCNT2

N-, O-Glycan and glycolipid biosynthesis

I antigen Siaa2,3Galb1,3GalNAca1-

ST3GAL1

O-Glycan biosynthesis

Ser/Thr

FUT2

N-, O-Glycan and glycolipid biosynthesis

H antigen

GALNT6

O-Glycan biosynthesis

GalNAca1-Ser/Thr

GALNT8

O-Glycan biosynthesis

GalNAca1-Ser/Thr

GALNT10

O-Glycan biosynthesis

GalNAca1-Ser/Thr

GALNT12

O-Glycan biosynthesis

GalNAca1-Ser/Thr

GALNT14

O-Glycan biosynthesis

GalNAca1-Ser/Thr

GALNTL2

Unknown

 

B3GALT5

N-, O-Glycan and glycolipid biosynthesis

Galb1,3GlcNAc-R, SSEA-3

B3GALT1

N-, O-Glycan and glycolipid biosynthesis N- and O-Glycan, keratan sulfate

Galb1,3GlcNAc-R

B3GNT2

biosynthesis

polylactosamine

  1. The fourteen glycosyltransferases with identified correspondences between expression, network, and glycan signatures were allocated to biosynthetic pathways, using the KEGG GLYCAN database with modifications. The names of the pathways are listed. See also additional file 12 for the detailed pathways of notable glycosyltransferases, according to the KEGG GLYCAN database.