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Figure 1 | BMC Systems Biology

Figure 1

From: Functional pathway mapping analysis for hypoxia-inducible factors

Figure 1

A mapped HIF functional pathway with zebrafish as the query species and humans as the reference species is shown. The initial HIF pathway was acquired from the KEGG database, and the mapped functional pathway between zebrafish and humans was constructed on the basis of the homologous relationship. The novel parameters OrthRate and ParaRate are proposed for indicating the degree of functional conservation across species regarding a specific biological function. Higher ParaRates are shown within rectangular boxes with darker backgrounds. The rectangular boxes with white background represent no orthologous relationship at the compared node between 2 species.

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