Figure 4From: DBAC: A simple prediction method for protein binding hot spots based on burial levels and deeply buried atomic contactsTwo residues that are difficult to classify in our data set. Two residues that are difficult to classify in our data set. In (a), ARG-17 of BPTI (in yellow) in bovine chymotrypsin (in green)-BPTI complex [PDB:1CBW] is shown. This residue is a non hot spot residue (∆∆G=0.5 kcal/mol) with an extremely low SASA (8.0 Å2). In (b), TYR-29 of barstar (in yellow) in barnase (in green)-barstar complex [PDB:1BRS] is shown. This residue is a hot spot residue (∆∆G=3.4 kcal/mol), but it has a large SASA (64.12 Å2). These two residues have been correctly classified by our method. The dashed lines in the figures are Type-II atomic contacts (candidates of hydrogen bonds).Back to article page