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Table 1 Performance of our method (DBAC) in comparison with using all atomic contact (AC) and Robetta

From: DBAC: A simple prediction method for protein binding hot spots based on burial levels and deeply buried atomic contacts

Method Sensitivity Precision Specificity Accuracy F1 p-value
DBAC 0.58 0.6744 0.9327 0.8643 0.6237 3.0280×10–12
AC 0.32 0.5333 0.9327 0.8140 0.4 1.2849×10–5
Robetta 0.44 0.3667 0.8173 0.7442 0.4 5.3817×10–8
FoldX 0.5 0.4630 0.8606 0.7907 0.4808 6.2451×10–11