Table 1 Protein pairs included in the top-30 DEPs
Protein 1 | Name of Protein 1 | Protein 2 | Name of Protein 2 | P-value | G-mean | Significance |
|---|---|---|---|---|---|---|
NUTF2 | nuclear transport factor 2 | NUP62 | nucleoporin 62kDa | 7.5E-06 | 0.37 | 1.90 |
CDC7 | cell division cycle 7 homolog (S. cerevisiae) | MCM3 | minichromosome maintenance complex component 3 | 1.3E-05 | 0.34 | 1.66 |
VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 | 4.3E-05 | 0.36 | 1.56 |
HSPA8 | heat shock 70kDa protein 8 | TADA3L | transcriptional adaptor 3 | 1.0E-05 | 0.26 | 1.29 |
TNR | tenascin R (restrictin, janusin) | NFASC | neurofascin | 1.6E-04 | 0.33 | 1.25 |
ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | PRKCI | protein kinase C, iota | 6.4E-05 | 0.28 | 1.17 |
PDGFRB | platelet-derived growth factor receptor, beta polypeptide | SNX2 | sorting nexin 2 | 8.7E-05 | 0.28 | 1.14 |
RFC5 | replication factor C (activator 1) 5, 36.5kDa | POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 5.5E-05 | 0.27 | 1.13 |
NFIB | nuclear factor I/B | RFX1 | regulatory factor X, 1 (influences HLA class II expression) | 3.4E-04 | 0.32 | 1.12 |
EIF3I | eukaryotic translation initiation factor 3, subunit I | SUMO4 | SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae) | 1.7E-05 | 0.23 | 1.09 |
COL17A1 | collagen, type XVII, alpha 1 | LAD1 | ladinin 1 | 3.9E-04 | 0.31 | 1.07 |
IRS1 | insulin receptor substrate 1 | UBTF | upstream binding transcription factor, RNA polymerase I | 4.5E-04 | 0.32 | 1.05 |
CAV1 | caveolin 1, caveolae protein, 22kDa | TRAF6 | TNF receptor-associated factor 6 | 1.0E-04 | 0.26 | 1.05 |
RPS14 | ribosomal protein S14 | RPS27A | ribosomal protein S27a | 3.2E-03 | 0.41 | 1.03 |
HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 4.1E-05 | 0.23 | 1.02 |
TAF4 | TATA box binding protein (TBP)-associated factor, 135kDa | CBX3 | chromobox homolog 3 | 1.0E-03 | 0.34 | 1.01 |
VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) | VPS45 | vacuolar protein sorting 45 homolog (S. cerevisiae) | 2.4E-04 | 0.28 | 1.00 |
ATP5F1 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 | ATP5J2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 | 8.1E-05 | 0.24 | 0.99 |
POLR2G | polymerase (RNA) II (DNA directed) polypeptide G | SF3B2 | splicing factor 3b, subunit 2, 145kDa | 2.6E-03 | 0.38 | 0.98 |
PDPK1 | 3-phosphoinositide dependent protein kinase-1 | PRKCQ | protein kinase C, theta | 4.5E-05 | 0.22 | 0.97 |
EP300 | E1A binding protein p300 | TF | transferrin | 5.3E-04 | 0.30 | 0.97 |
RPS5 | ribosomal protein S5 | RPL28 | ribosomal protein L28 | 1.4E-03 | 0.34 | 0.96 |
ELK1 | ELK1, member of ETS oncogene family | GRB10 | growth factor receptor-bound protein 10 | 9.7E-04 | 0.32 | 0.96 |
RPS13 | ribosomal protein S13 | ATAD3A | ATPase family, AAA domain containing 3A | 5.8E-05 | 0.23 | 0.95 |
PABPC1 | poly(A) binding protein, cytoplasmic 1 | RPS4Y1 | ribosomal protein S4, Y-linked 1 | 2.5E-03 | 0.37 | 0.95 |
PRPF4 | PRP4 pre-mRNA processing factor 4 homolog (yeast) | PPIH | peptidylprolyl isomerase H (cyclophilin H) | 6.5E-04 | 0.29 | 0.93 |
ZFP36 | zinc finger protein 36, C3H type, homolog (mouse) | EIF2C4 | eukaryotic translation initiation factor 2C, 4 | 6.3E-04 | 0.29 | 0.93 |
RPLP2 | ribosomal protein, large, P2 | RPL29 | ribosomal protein L29 | 1.2E-03 | 0.32 | 0.93 |
HSF1 | heat shock transcription factor 1 | STIP1 | stress-induced-phosphoprotein 1 | 1.5E-04 | 0.24 | 0.92 |
GSK3B | glycogen synthase kinase 3 beta | FUS | fused in sarcoma | 2.7E-03 | 0.35 | 0.91 |