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Table 1 Protein pairs included in the top-30 DEPs

From: Differentially co-expressed interacting protein pairs discriminate samples under distinct stages of HIV type 1 infection

Protein 1 Name of Protein 1 Protein 2 Name of Protein 2 P-value G-mean Significance
NUTF2 nuclear transport factor 2 NUP62 nucleoporin 62kDa 7.5E-06 0.37 1.90
CDC7 cell division cycle 7 homolog (S. cerevisiae) MCM3 minichromosome maintenance complex component 3 1.3E-05 0.34 1.66
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) ARFGAP1 ADP-ribosylation factor GTPase activating protein 1 4.3E-05 0.36 1.56
HSPA8 heat shock 70kDa protein 8 TADA3L transcriptional adaptor 3 1.0E-05 0.26 1.29
TNR tenascin R (restrictin, janusin) NFASC neurofascin 1.6E-04 0.33 1.25
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 PRKCI protein kinase C, iota 6.4E-05 0.28 1.17
PDGFRB platelet-derived growth factor receptor, beta polypeptide SNX2 sorting nexin 2 8.7E-05 0.28 1.14
RFC5 replication factor C (activator 1) 5, 36.5kDa POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 5.5E-05 0.27 1.13
NFIB nuclear factor I/B RFX1 regulatory factor X, 1 (influences HLA class II expression) 3.4E-04 0.32 1.12
EIF3I eukaryotic translation initiation factor 3, subunit I SUMO4 SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae) 1.7E-05 0.23 1.09
COL17A1 collagen, type XVII, alpha 1 LAD1 ladinin 1 3.9E-04 0.31 1.07
IRS1 insulin receptor substrate 1 UBTF upstream binding transcription factor, RNA polymerase I 4.5E-04 0.32 1.05
CAV1 caveolin 1, caveolae protein, 22kDa TRAF6 TNF receptor-associated factor 6 1.0E-04 0.26 1.05
RPS14 ribosomal protein S14 RPS27A ribosomal protein S27a 3.2E-03 0.41 1.03
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 4.1E-05 0.23 1.02
TAF4 TATA box binding protein (TBP)-associated factor, 135kDa CBX3 chromobox homolog 3 1.0E-03 0.34 1.01
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) 2.4E-04 0.28 1.00
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 8.1E-05 0.24 0.99
POLR2G polymerase (RNA) II (DNA directed) polypeptide G SF3B2 splicing factor 3b, subunit 2, 145kDa 2.6E-03 0.38 0.98
PDPK1 3-phosphoinositide dependent protein kinase-1 PRKCQ protein kinase C, theta 4.5E-05 0.22 0.97
EP300 E1A binding protein p300 TF transferrin 5.3E-04 0.30 0.97
RPS5 ribosomal protein S5 RPL28 ribosomal protein L28 1.4E-03 0.34 0.96
ELK1 ELK1, member of ETS oncogene family GRB10 growth factor receptor-bound protein 10 9.7E-04 0.32 0.96
RPS13 ribosomal protein S13 ATAD3A ATPase family, AAA domain containing 3A 5.8E-05 0.23 0.95
PABPC1 poly(A) binding protein, cytoplasmic 1 RPS4Y1 ribosomal protein S4, Y-linked 1 2.5E-03 0.37 0.95
PRPF4 PRP4 pre-mRNA processing factor 4 homolog (yeast) PPIH peptidylprolyl isomerase H (cyclophilin H) 6.5E-04 0.29 0.93
ZFP36 zinc finger protein 36, C3H type, homolog (mouse) EIF2C4 eukaryotic translation initiation factor 2C, 4 6.3E-04 0.29 0.93
RPLP2 ribosomal protein, large, P2 RPL29 ribosomal protein L29 1.2E-03 0.32 0.93
HSF1 heat shock transcription factor 1 STIP1 stress-induced-phosphoprotein 1 1.5E-04 0.24 0.92
GSK3B glycogen synthase kinase 3 beta FUS fused in sarcoma 2.7E-03 0.35 0.91
  1. Here, significance is “-log(P-value) × G-mean”.