SigCS base: an integrated genetic information resource for human cerebral stroke

BMC Systems Biology

Table 2 Statistics on the information in SigCS base

No.	Stroke or Etiology	# of Genes	# of Variants	# of Sig. Pathways^*
1	Stroke	236	1609	18
2	Atherosclerosis	200	891	19
3	Cardiovascular disease	143	501	9
4	Coagulation, blood	47	732	19
5	Estrogen	353	851	6
6	Hypercysteinemia	90	118	2
7	Hyperlipidemia	102	333	10
8	Hypertension	521	2177	13
9	Intracranial arteriovenous malformations (including intracranial aneurysm)	60	182	11
10	Inflammation	696	1354	94
11	Obesity	412	1121	27
12	Diabetes mellitus, type 2	208	1603	19
Total	Stroke + All etiologies	3068(1943)^†	11472	247(165)^†

* Pathways with the FDR q-values of less than 0.05.
† Numbers in ( ) are counts for non-redundant genes or pathways over the etiologies.

ISSN: 1752-0509