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Table 1 Reprogramming rate and average reprogramming time of cells from different levels

From: Novel Markov model of induced pluripotency predicts gene expression changes in reprogramming

Initial cell type

First level

Second level

Third level

Fourth level

Reprogramming rate (SRM model)

0.024%

0.26%

3.13%

100%

Death rate

99.98%

99.74%

96.87%

0%

Average reprogramming time (cell cycles)

8.72

6.00

3.42

0

  1. When knockdown of somatic transcription factors, reprogramming rate from first level is 0.027% and average reprogramming time is 7.16 cell cycles. In reprogramming Ising model, reprogramming rate from first level is 0.025%.