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Table 1 Reprogramming rate and average reprogramming time of cells from different levels

From: Novel Markov model of induced pluripotency predicts gene expression changes in reprogramming

Initial cell type First level Second level Third level Fourth level
Reprogramming rate (SRM model) 0.024% 0.26% 3.13% 100%
Death rate 99.98% 99.74% 96.87% 0%
Average reprogramming time (cell cycles) 8.72 6.00 3.42 0
  1. When knockdown of somatic transcription factors, reprogramming rate from first level is 0.027% and average reprogramming time is 7.16 cell cycles. In reprogramming Ising model, reprogramming rate from first level is 0.025%.