From: A comprehensive network and pathway analysis of candidate genes in major depressive disorder
Ingenuity canonical pathways | Observed* | P BH $ |
---|---|---|
cAMP-mediated signaling | 23 | 6.31 × 10-16 |
G-protein coupled receptor signaling | 31 | 5.01 × 10-15 |
Serotonin receptor signaling | 12 | 6.31 × 10-15 |
Corticotropin releasing hormone signaling | 14 | 7.94 × 10-11 |
Dopamine receptor signaling | 11 | 3.80 × 10-9 |
Glucocorticoid receptor signaling | 17 | 1.35 × 10-8 |
PXR/RXR activation | 10 | 2.29 × 10-8 |
Amyotrophic lateral sclerosis signaling | 11 | 5.89 × 10-8 |
Neuropathic pain signaling on dorsal horn neurons | 11 | 5.89 × 10-8 |
Relaxin signaling | 12 | 1.02 × 10-7 |
CREB signaling in neurons | 13 | 1.62 × 10-7 |
Tryptophan metabolism | 11 | 6.61 × 10-7 |