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Table 5 DIP Core- statistical properties, from FANMOD

From: Biological network motif detection and evaluation

Label

Freq(Original)

Mean-Freq (Random)

S-Dev(Random)

Z-score

P-value

C^

1.46%

5.9e-005%

3.04e-006

4813.3

< 10-3

CN

10.21%

0.01%

< 10-6

289.09

< 10-3

CF

48.69%

42.22%

< 10-6

17.31

< 10-3

C~

0.48%

0.00%

0

undefined

< 10-3

Cr

0.47%

0.23%

< 10-6

16.28

< 10-3

CR

38.65%

57.54%

< 10-6

-52.17

> 10-2

  1. Each type of 4-node subgraph shows its significance based on its structural uniqueness. The label is generated by Nauty program [24] and the corresponding shape is shown in Figure 1. All types except CR are structural network motifs by definition.