Method
|
Network size
|
p-value of chi square testa
|
TPR (%)b
|
# misclass.c
|
TP
|
O/Ed
|
---|
iBMA-prior
|
8000
|
7.75E-65
|
15.62
|
10198
|
323
|
2.41
|
iBMA-shortlist
|
35995
|
1.02E-59
|
10.99
|
14581
|
818
|
1.70
|
Lirnet
|
10491
|
1.90E-03
|
8.42
|
10080
|
132
|
1.30
|
- a The p-value of Pearson’s chi-square test measures the strength of association between an inferred network and the Yeastract database.
- b True positive rate (TPR) is defined as the proportion of inferred regulatory relationships that are documented in Yeastract.
- c The number of misclassified cases is the sum of false positives and false negatives.
- d The O/E ratio is the number of folds the observed number of recovered relationships (i.e., TP) in excess of the expected count of recovery by chance.