Skip to main content

Table 2 An overview of the biological experiments

From: Towards a quantitative understanding of the MITF-PIAS3-STAT3 connection

Description Reference
1. Temporal development of ERK and RSK1 kinase activity [14]Figure 5B
2. Distribution between MITF phosphorylation before stimulation [14]Figure 1 and 2
3. Temporal development of MITF phosphorylation states after stimulation [14]Figure 1 and 2
4. Temporal development of MITF degradation [14]Figure 1 and 2
5. MITF activity in response to PIAS3 transfection [19]Figure 6
6. Amount of MITF-PIAS3 complex in response to activation [20] Figure 2A
7. Amount of MITF-PIAS3 complex in response to activation with transfected MITF and PIAS3 [20] Figure 2B
8. MITF activity in response to transfection of constitutively active RSK1 [20] Figure 3A
9. MITF activity in response to PIAS3 [20] Figure 3B, left, black
10. MITF activity in response to transfection of PIAS3 and active RSK1 [20] Figure 3B, left, grey
11. Activity of a MITF-S409A mutant in response to PIAS3 [20] Figure 3B, right, black
12. Activity of a MITF-S409A mutant in response to transfection of PIAS3 and active RSK1 [20] Figure 3B, right, grey
13. Activity of MITF in response to transfection of PIAS3 [20] Figure 6
14. Activity of MITF-S73D mutant in response to transfection of PIAS3 [20] Figure 6
15. Activity of MITF-S409D mutant in response to transfection of PIAS3 [20] Figure 6
16. Activity of MITF-S73/409D mutant in response to transfection of PIAS3 [20] Figure 6
17. MITF-PIAS3 association in response to activation [22] Figure 3A
18. S409A mutated MITF-PIAS3 association in response to activation [22] Figure 3A
19. STAT3 activity in response to activation [22] Figure 3B
20. STAT3 activity in response to activation with transfected PIAS3 [22] Figure 3B
21. STAT3 activity in response to activation with transfected PIAS3 and small amount of MITF [22] Figure 3B
22. STAT3 activity in response to activation with transfected PIAS3 and large amount of MITF [22] Figure 3B
23. STAT3 activity in response to activation with transfected PIAS3 and small amount of S-409A mutated MITF [22] Figure 3B
24. STAT3 activity in response to activation with transfected PIAS3 and large amount of S409A mutated MITF [22] Figure 3B
25. MITF activity in response to transfection of Y705F mutated STAT3 and STAT3-C [22] Figure 4B
26. MITF and STAT3 activity in response to activation compared between wild type and mutated MITF (unable to bind PIAS3) [22] Figure 6D and E
27. STAT3 activity in response to transfection of MITF or S409D MITF mutation [22] Figure 7C
28. MITF activity in response to transfection of STAT3-C [22] Figure 7D
  1. The numbers assigned to each experiment in the table is used to identify the experiment throughout this paper. For each experiment the reference and the figure number within the reference are provided.