Figure 2

Triad significance profiles (TSPs) of bio-information processing networks. Panel A: E.coli (2004). TRN of E.coli as firstly published in[32, 34] (N = 423 operons, L = 519 regulations plus SL = 59 self-regulations). Yeast (2004) TRN of budding yeast[6] (N = 688 genes, L = 1079 regulations[32, 35]). Panel B: C.elegans neural network[33] (N = 279 neurons, L = 2990 synapses). M.tuberculosis TRN[12] (N = 1624 genes,[36]L = 3169 regulations plus SL = 43 self-regulations). Panel C: E.coli (2011). Updated TRN of E.coli based on RegulonDB, release 7.2, dated on May, 2011 (N = 1037 operons, L = 2574 regulations plus SL = 113 self-regulations). B.subtilis (2011), updated TRN of B.subtilis, based on DBTBS database[9], (accessed in October, 2011) (N = 814 operons, L = 1294 regulations plus SL = 80 self-regulations).