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Figure 5 | BMC Systems Biology

Figure 5

From: Predicting and characterizing selective multiple drug treatments for metabolicdiseases and cancer

Figure 5

Results on cancer vs human selectivity problem. Left panel: The iterative application of the algorithm to thecancer vs human networks finds 21 solutions before becoming unfeasible(magenta line). Including the possibility of inhibiting an additional target,other 31 solutions are found (blue line). Right panel: The bars countthe number of solutions which stop the biomass metabolite in the cancermetabolism (same color code). Solutions have been classified according to thenecessity or less of the inhibition of an additional target (see Tables 3, Additional file 3: Table S3 formore details).

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