Figure 3

Cell-specific CA04-induced functional enrichment. Cell-type specific enrichment of CA04-induced up-regulated DE transcripts is shown for day 3 (left) and day 7 (right) post-infection. Enriched cell-type-specific IPA annotations (FDR-adjusted P-value < 0.05) were sorted according to function (categories shown to the left of each panel) and cell-type (shown at the top of each panel), and the level of enrichment was illustrated by a heat map showing the -log₁₀-adjusted P-value for each annotation. Because P-values associated with highly related annotations (e.g., ‘Cell Movement’, ‘Chemotaxis’ and ‘Trafficking’) were grouped together, a cell type could be enriched several times within a particular category. Cell types with the highest enriched categories are shown in boldface (top), whereas cell types for which no categories were enriched are shown in grey. All other cell types, exhibiting intermediate levels of enrichment in various categories, are represented in normal black text. A color-key for the heat map is shown at the lower left of the figure, in which day 3 P-values are represented by the range above the color bar and day 7 P-values are indicated below the bar.