Figure 6

Meq interactome showing previously published and novel interactions identified by ChIP experiments and GO based modeling of Meq interacting proteins. Meq interactome based on combined data from proteins identified by chromatin immunoprecipitation (ChIP) experiments (see Methods) and published literature. Differential expression is shown for proteins identified by ChIP. (A). Meq interactome converted to a GO functional network showing the physiological processes that Meq directly affects are consistent with neoplasia. Circle size represents effect size based on numbers of proteins associated with that GO annotation (B).