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Figure 3 | BMC Systems Biology

Figure 3

From: Dynamics of p53 and NF-κB regulation in response to DNA damage and identification of target proteins suitable for therapeutic intervention

Figure 3

Feed-forward loops (FFLs) and Feedback loops (FLs) in the logical model. Coherent FFLs of type 1 with AND logic (A-E), or OR logic (F-K), respectively; coherent FFLs of type 2 with AND logic (L, M); coherent FFLs of type 3 (N-R); coherent FFLs of type 4 (S-Ä), and an incoherent FFL of type 2 (Ö). Among negative FLs (a-g), only the functional (in the logical model) are shown. Letters in circles: P = phosphorylation, S = sumoylation.

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