Skip to main content

Table 2 The cTBFSs mapped to the promoters of the 418 genes differentially expressed in ESCC

From: Identification of estrogen responsive genes using esophageal squamous cell carcinoma (ESCC) as a model

ERE Category   C1+C3 C1 C2 C3 C4
Number of Genes   202 56 72 146 144
   Genes % Genes % Genes % Genes % Genes %
cTFBS38 V$AREB6_01|V$YY1_01|V$CETS1P54_01|V$E2A_Q6 17 8.42% 8 14.29% 9 12.50% 9 6.16% 0 0.00%
cTFBS39 V$AREB6_01|V$FREAC4_01|V$EBOX_Q6_01|V$E2A_Q6 16 7.92% 11 19.64% 7 9.72% 5 3.42% 0 0.00%
cTFBS44 V$TAXCREB_02|V$AREB6_01|V$CETS1P54_01|V$EBOX_Q6_01|V$CREB_Q3|V$E2A_Q6 16 7.92% 9 16.07% 7 9.72% 7 4.79% 0 0.00%
cTFBS43 V$TAXCREB_02|V$AREB6_01|V$EBOX_Q6_01|V$CREB_Q3|V$E2A_Q6 19 9.41% 9 16.07% 11 15.28% 10 6.85% 0 0.00%
cTFBS17 V$TAXCREB_02|V$FREAC4_01|V$E2A_Q6 18 8.91% 10 17.86% 8 11.11% 8 5.48% 0 0.00%
cTFBS34 V$TAXCREB_02|V$AREB6_01|V$CREB_Q3|V$E2A_Q6 22 10.89% 10 17.86% 14 19.44% 12 8.22% 0 0.00%
cTFBS33 V$TAXCREB_02|V$AREB6_01|V$ELK1_01|V$CREB_Q3 18 8.91% 8 14.29% 8 11.11% 10 6.85% 0 0.00%
cTFBS41 V$TAXCREB_02|V$AREB6_01|V$CETS1P54_01|V$CREB_Q3|V$E2A_Q6 17 8.42% 9 16.07% 9 12.50% 8 5.48% 0 0.00%
cTFBS32 V$TAXCREB_02|V$ELK1_01|V$EBOX_Q6_01|V$CREB_Q3 19 9.41% 10 17.86% 8 11.11% 9 6.16% 1 0.69%
cTFBS23 V$AREB6_01|V$ELK1_01|V$CREB_Q3 19 9.41% 8 14.29% 8 11.11% 11 7.53% 1 0.69%
cTFBS35 V$TAXCREB_02|V$AREB6_01|V$EBOX_Q6_01|V$CREB_Q3 21 10.40% 11 19.64% 11 15.28% 10 6.85% 1 0.69%
cTFBS26 V$AREB6_01|V$FREAC4_01|V$E2A_Q6 19 9.41% 13 23.21% 7 9.72% 6 4.11% 1 0.69%
cTFBS37 V$AREB6_01|V$CETS1P54_01|V$CREB_Q3|V$E2A_Q6 19 9.41% 10 17.86% 9 12.50% 9 6.16% 1 0.69%
cTFBS16 V$TAXCREB_02|V$FREAC4_01|V$CETS1P54_01 20 9.90% 14 25.00% 10 13.89% 6 4.11% 1 0.69%
cTFBS36 V$TAXCREB_02|V$EBOX_Q6_01|V$CREB_Q3|V$E2A_Q6 24 11.88% 12 21.43% 12 16.67% 12 8.22% 1 0.69%
cTFBS42 V$TAXCREB_02|V$AREB6_01|V$CETS1P54_01|V$EBOX_Q6_01|V$E2A_Q6 21 10.40% 12 21.43% 12 16.67% 9 6.16% 1 0.69%
cTFBS22 V$FREAC4_01|V$CETS1P54_01|V$EBOX_Q6_01 18 8.91% 13 23.21% 10 13.89% 5 3.42% 1 0.69%
cTFBS40 V$AREB6_01|V$EBOX_Q6_01|V$CREB_Q3|V$E2A_Q6 21 10.40% 10 17.86% 11 15.28% 11 7.53% 1 0.69%
cTFBS21 V$FREAC4_01|V$CETS1P54_01|V$E2A_Q6 18 8.91% 12 21.43% 7 9.72% 6 4.11% 1 0.69%
cTFBS28 V$AREB6_01|V$EBOX_Q6_01|V$CREB_Q3 23 11.39% 12 21.43% 11 15.28% 11 7.53% 2 1.39%
cTFBS20 V$TAXCREB_02|V$EBOX_Q6_01|V$CREB_Q3 27 13.37% 14 25.00% 13 18.06% 13 8.90% 2 1.39%
cTFBS31 V$TAXCREB_02|V$ELK1_01|V$CETS1P54_01|V$EBOX_Q6_01 23 11.39% 14 25.00% 16 22.22% 9 6.16% 2 1.39%
cTFBS27 V$AREB6_01|V$CREB_Q3|V$E2A_Q6 24 11.88% 11 19.64% 14 19.44% 13 8.90% 2 1.39%
cTFBS8 V$FREAC4_01|V$EBOX_Q6_01 22 10.89% 15 26.79% 13 18.06% 7 4.79% 3 2.08%
cTFBS18 V$TAXCREB_02|V$AREB6_01|V$CREB_Q3 27 13.37% 12 21.43% 17 23.61% 15 10.27% 3 2.08%
cTFBS24 V$AREB6_01|V$CETS1P54_01|V$CREB_Q3 24 11.88% 11 19.64% 9 12.50% 13 8.90% 3 2.08%
cTFBS13 V$TAXCREB_02|V$ELK1_01|V$CREB_Q3 28 13.86% 12 21.43% 11 15.28% 16 10.96% 3 2.08%
cTFBS9 V$AREB6_01|V$FREAC4_01 26 12.87% 15 26.79% 11 15.28% 11 7.53% 4 2.78%
cTFBS19 V$TAXCREB_02|V$CREB_Q3|V$E2A_Q6 30 14.85% 14 25.00% 15 20.83% 16 10.96% 4 2.78%
cTFBS7 V$FREAC4_01|V$E2A_Q6 25 12.38% 14 25.00% 9 12.50% 11 7.53% 4 2.78%
cTFBS30 V$EBOX_Q6_01|V$CREB_Q3|V$E2A_Q6 27 13.37% 13 23.21% 13 18.06% 14 9.59% 4 2.78%
cTFBS1 V$ELK1_01|V$CREB_Q3 32 15.84% 12 21.43% 11 15.28% 20 13.70% 5 3.47%
cTFBS6 V$FREAC4_01|V$CETS1P54_01 27 13.37% 17 30.36% 12 16.67% 10 6.85% 5 3.47%
cTFBS15 V$TAXCREB_02|V$CETS1P54_01|V$EBOX_Q6_01 34 16.83% 18 32.14% 21 29.17% 16 10.96% 5 3.47%
cTFBS25 V$AREB6_01|V$CETS1P54_01|V$E2A_Q6 30 14.85% 16 28.57% 16 22.22% 14 9.59% 5 3.47%
cTFBS10 V$AREB6_01|V$CREB_Q3 31 15.35% 13 23.21% 17 23.61% 18 12.33% 6 4.17%
cTFBS14 V$TAXCREB_02|V$CETS1P54_01|V$E2A_Q6 33 16.34% 15 26.79% 19 26.39% 18 12.33% 6 4.17%
cTFBS12 V$EBOX_Q6_01|V$CREB_Q3 32 15.84% 16 28.57% 15 20.83% 16 10.96% 7 4.86%
cTFBS29 V$AREB6_01|V$EBOX_Q6_01|V$E2A_Q6 38 18.81% 16 28.57% 21 29.17% 22 15.07% 8 5.56%
cTFBS2 V$ELK1_01|V$EBOX_Q6_01 36 17.82% 17 30.36% 18 25.00% 19 13.01% 9 6.25%
cTFBS3 V$CETS1P54_01|V$CREB_Q3 38 18.81% 15 26.79% 14 19.44% 23 15.75% 10 6.94%
cTFBS4 V$CETS1P54_01|V$EBOX_Q6_01 41 20.30% 21 37.50% 24 33.33% 20 13.70% 11 7.64%
cTFBS5 V$TAXCREB_02|V$CREB_Q3 43 21.29% 18 32.14% 23 31.94% 25 17.12% 12 8.33%
cTFBS11 V$AREB6_01|V$E2A_Q6 50 24.75% 23 41.07% 25 34.72% 27 18.49% 16 11.11%
  1. 44 significant cTFBSs consisting of 12 doublet cTFBS, 18 triplet cTFBS, 10 4-element cTFBS, 3 5-element cTFBS and 1 6-element cTFBS were identified.