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Figure 1 | BMC Systems Biology

Figure 1

From: A model of estrogen-related gene expression reveals non-linear effects in transcriptional response to tamoxifen

Figure 1

General scheme of the processes included in the model of ER-dependent gene expression. (A) Reactions of ER dimerisation and binding with two types of ligands - natural hormone (H) and an inhibitor (I); (B) Binding of dimeric forms of receptor-ligand complexes with ERE; (C) Synthesis and degradation of mRNA (r) and protein (p). The detailed description of the scheme is given in the text.

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