From: Incremental parameter estimation of kinetic metabolic network models
Simultaneous method | Incremental method | |||
---|---|---|---|---|
| min Φ S | min Φ C | min Φ S | |
CPU time (sec) | 17.86 h | 534.83 ± 22.12 | 71.88 ± 6.33 | 1.17 ± 0.12 |
44.63 h | ||||
eSSM GO iterations | 254 | 3494 ± 348 | 12 ± 2 | 10 ± 3 |
426 | ||||
Parameter error (%) | 75.42 | 54.36 ± 4.47 | 75.77 ± 6.11 × 10-3 | 51.15 ± 1.38 × 10-3 |
34.98 | ||||
Φ C | 3.62 × 10 -2 | 6.06 × 10-2 ± 1.14 × 10-3 | 3.52 × 10-2 ± 9.50 × 10-9 | 4.76 × 10-2 ± 3.81 × 10-7 |
3.27 × 10 -2 | ||||
Φ S | 2.06 × 10-1 | 1.34 × 10-1 ± 6.02 × 10-4 | 1.64 × 10-1 ± 2.23 × 10-5 | 1.38 × 10-1 ± 2.26 × 10-10 |
1.60 × 10-1 |