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Table 2 Comparison of the network overlap for the time- and condition-dependent minimal networks between AdaM and MADE

From: Integration of time-resolved transcriptomics data with flux-based methods reveals stress-induced metabolic adaptation in Escherichia coli

Time in min

Cold

Heat

Random

10

62.8

62.6

 

20

66.7

68.5

 

30

67.8

69.8

 

40

63.8

68.3

 

50

62.0

67.9

 

60

69.0

63.2

 

70

70.6

70.2

 

average

66.1

67.2

52.3

  1. Given is the overlap in % of reactions included in the networks extracted by our approach and by MADE with respect to the smaller network. The average value for all time-dependent cold- and heat-shock specific networks are significantly higher than the values for a randomly drawn set of reactions of the same size.