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Table 2 Model predicted normalized growth values (with respect to wild type growth at 26°C) for Y. pestis after imposition of additional constraints based on mRNA expression data

From: Genome-level transcription data of Yersinia pestis analyzed with a New metabolic constraint-based approach

Form of stress

Normalized growth range

Temperature change 26°C to 37°C, YP 201, [Ca2+]≈ 0 mM

0.13-0.13

Temperature change 26°C to 37°C, KIM5,[Ca2+]= 4 mM

1.0-1.0

Antibiotics: Streptomycin

0.50-0.50

Antibiotics: Chloramphenicol

0.47-0.47