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Table 2 Model predicted normalized growth values (with respect to wild type growth at 26°C) for Y. pestis after imposition of additional constraints based on mRNA expression data

From: Genome-level transcription data of Yersinia pestis analyzed with a New metabolic constraint-based approach

Form of stress Normalized growth range
Temperature change 26°C to 37°C, YP 201, [Ca2+]≈ 0 mM 0.13-0.13
Temperature change 26°C to 37°C, KIM5,[Ca2+]= 4 mM 1.0-1.0
Antibiotics: Streptomycin 0.50-0.50
Antibiotics: Chloramphenicol 0.47-0.47