Prediction of IL-2 receptor as a possible off-target of torcetrapib. (A) Docked complex of IL-2 receptor (PDB code 4HCV) and compound 13 J in the best docking pose. (B) Docked complex of IL-2 receptor and torcetrapib in the best docking pose. Compound 13 J and torcetrapib were in the stick representation, whilst the amino acid residues of IL-2 receptor were displayed by solid ribbon style in the line representation. C, H, O, N and F were colored with gray, white, red, blue and brown, respectively.