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Table 3 Residual sum of squares values for each reaction

From: Dynamic regulatory on/off minimization for biological systems under internal temporal perturbations

Method

Reaction

     
 

v1

v2

v3

v4

v5

v6

v7

DFBA

5.93

57.44

7.23

6.47

38.49

19.14

0.07

M-DFBA

64.73

175.32

154.96

149.77

76.70

16.70

0.06

Flux-based M-DFBA

58.60

142.74

127.75

131.11

67.76

16.47

0.03

M-DFBA CF

53.91

143.06

125.41

126.05

67.09

16.85

0.06

R-DFBA NLP

41.13

130.15

113.79

111.48

53.72

16.85

0.06

Flux-based R-DFBA NLP

54.21

187.37

173.83

164.65

82.47

16.30

0.04

R-DFBA CF NLP

51.68

144.16

143.96

145.26

70.02

16.85

0.06

R-DFBA MINLP

63.95

169.37

158.54

158.91

73.16

17.78

0.06

Flux-based R-DFBA MINLP

47.99

108.16

99.58

102.80

61.20

16.61

0.05

R-DFBA CF MINLP

25.91

61.38

59.78

60.24

44.04

14.36

0.02

  1. The discrepancy between the kinetic modeling results and the results obtained from the different DFBA-based approaches is quantified based on the residual sum of squares
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BMC Systems Biology

ISSN: 1752-0509

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