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Table 1 PPI z-score and the coverage of gene sets involved in regulatory motifs

From: Crosstalk between transcription factors and microRNAs in human protein interaction network

  Single-regulation Co- regulation Crosstalk Independent
  TF-TF    
z-score 62.17 62.10 -0.80 -27.32
coverage 16.19% 4.31% 96.65% 83.81%
z-score* 56.43 51.37 11.37 -15.14
coverage* 6.72% 0.92% 70.60% 93.28%
  miRNA-miRNA    
z-score 35.37 38.15 1.52 -20.79
coverage 25.68% 9.14% 96.60% 74.32%
z-score* 34.74 32.16 14.37 -12.08
coverage* 10.79% 2.15% 69.08% 89.21%
  TF-miRNA    
z-score - 62.44 -0.09 -55.91
coverage - 6.65% 97.42% 73.52%
z-score* - 47.94 15.71 -33.91
coverage* - 1.18% 70.49% 88.31%
  1. *The asterisk represents the filtered values. The upper limit of target gene size for filtration of TF-TF, miRNA-miRNA, and TF-miRNA motifs is 781, 789, and 789, respectively.
  2. *The coverage represents the ratio of gene pairs in regulatory motifs to all possible gene pairs in HPRD PIN.