Figure 2From: Systems analysis of the transcriptional response of human ileocecal epithelial cells to Clostridium difficile toxins and effects on cell cycle controlGene ontology categories associated with differentially expressed genes. A. The most significantly enriched GO categories (Fisher Exact Test, topGO elim algorithm [23], see Methods) at 2 h and 6 h are displayed in a heat map. The color intensity in each cell corresponds to the p-value (Fisher Exact Test) for the GO category that is enriched. The dendrograms were generated from a hierarchical clustering of GO Groups according to Resnik similarity [49]. B. The most significantly enriched GO categories at 24 h were determined similarly.Back to article page