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Table 1 Characteristics of the reconstructed metabolic models iLC915 and iSS884 of Pichia pastoris and stipitis, in comparison with the S. cerevisiae model iIN800 and iMM904

From: Genome-scale metabolic reconstructions of Pichia stipitis and Pichia pastoris and in silico evaluation of their potentials

Characteristics P. stipitis P. pastoris S. cerevisiae
  iSS884 iLC915 PpaMBEL1254 iPP668 iMM904 iIN800
Reactions 1332 1423 1202 1354 1312 1446
   Cytoplasm 824 790 604 623 635 906
   Mitochondria 207 205 155 163 180 161
   Peroxisome 60 64 66 66 63  
   Vacuole   12 6 3 3  
   ER   34 7 15 17  
   Golgi   4 8 4 2  
   Nucleus    17 16 18  
   Extracellular    11 12 7  
Transport 239 314 328 452 387 379
Metabolites 920 899 1147 1177 1168 1013
Gene coverage (%) 15.1 17.2 9.9 12.6 13.7 12.11
Coding genes 5841 5313 5313 5313 6607 6607
  1. Characteristics of the previous GEMs of P. pastoris are also included to compare with iLC915