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Table 1 Networks inferred from proteomics show significant enrichment in pathogen targets across many network inference parameters

From: Topological analysis of protein co-abundance networks identifies novel host targets important for HCV infection and pathogenesis

  Measure Group Background p-value Fold-enrichment
a CoA Degree 18% 18% 1.6E-01 1.0
  Betweenness 20% 17% 1.4E-07 1.2
  Clustering Coefficient 19% 17% 7.1E-03 1.1
  Closeness 19% 17% 1.2E-02 1.1
CoA + PPI Degree 35% 14% 2.2E-16 2.5
  Betweenness 46% 12% 2.2E-16 3.8
  Clustering Coefficient 31% 15% 2.2E-16 3.8
  Closeness 32% 15% 2.2E-16 2.1
  1. aCoA, co-abundance networks; CoA + PPI, co-abundance with protein-protein interactions