Figure 4

Edge consistency between interaction databases. Distribution of Edge Weights (the number of databases an interaction is found in) for all 63,276 interactions (A), and I2D-specific edge weights (the number of PPI datasets a PPI is found in) for 11,327 interactions form the I2D meta-database (B). Fractional Edge Overlap scores (proportion of interactions consistent beteen 2 databases) are represented as a hierarchically clustered heatmap (C). Note the heterogeneity, and overall poor concordance between different sources.