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Table 1 False positive model predictions that indicate model errors

From: Gap-filling analysis of the iJO1366 Escherichia coli metabolic network reconstruction for discovery of metabolic functions

Gene

Error

carA (b0032)

alternate pathway (CBMKr) gene functions not confirmed

carB (b0033)

alternate pathway (CBMKr) gene functions not confirmed

proB (b0242)

alternate pathway (NACODA) gene function not confirmed

proA (b0243)

alternate pathway (NACODA) gene function not confirmed

folD (b0529)

5fthf[c] and methf[c] may be essential

entD (b0583)

enter[c] may be essential

pyrD (b0945)

alternate pathway (DHORDfum) is an orphan reaction

pdxH (b1638)

pydx5p[c] may be essential

pgsA (b1912)

pgp120[p] - pgp181[p] may be essential

nrdA (b2234)

alternate pathway (RNDR1b – RNDR4b) gene functions not confirmed

nrdB (b2235)

alternate pathway (RNDR1b – RNDR4b) gene functions not confirmed

ptsI (b2416)

alternate pathway (GLCt2pp) glucose transport not confirmed

waaK (b3623)

colipa[e] may be essential

wzyE (b3793)

eca4colipa[e] may be essential

ubiE (b3833)

reactions AMMQLT8 and OMBZLM are blocked by gaps

ubiB (b3835)

alternate pathway (OPXHH3) is an orphan reaction

ppa (b4226)

isozymes, ppx (b2502) and surE (b2744), may be incorrect