Table 2 Enriched miRNA-associated functions in the GRN
From: Gene regulation is governed by a core network in hepatocellular carcinoma
Term | p-value | FDR |
|---|---|---|
Human embryonic stem cell (hESC) regulation | 8.46e-14 | 3.64e-12 |
Inflammation | 1.00e-08 | 2.15e-07 |
Hematopoiesis | 8.00e-08 | 1.15e-06 |
Apoptosis | 2.70e-07 | 2.90e-06 |
Cell cycle-related | 4.90e-07 | 3.81e-06 |
Hormones regulation | 5.60e-07 | 3.81e-06 |
Onco-miRNAs | 6.20e-07 | 3.81e-06 |
Immune response | 1.60e-06 | 8.60e-06 |
MiRNA tumor suppressors | 2.21e-06 | 1.06e-05 |
Cell death | 4.70e-06 | 2.02e-05 |
Cell differentiation | 2.40e-05 | 9.39e-05 |
Angiogenesis | 3.06e-05 | 1.10e-04 |
Cell motility | 2.34e-04 | 7.48e-04 |
Epithelial-mesenchymal transition | 2.60e-04 | 7.48e-04 |
HIV latency | 2.61e-04 | 7.48e-04 |
Brain development | 2.97e-04 | 7.99e-04 |
Chromatin remodeling | 3.36e-04 | 8.31e-04 |
Immune system | 3.48e-04 | 8.31e-04 |
Carbohydrate metabolism | 1.04e-03 | 2.35e-03 |
Akt pathway | 1.29e-03 | 2.78e-03 |
Bone regeneration | 1.72e-03 | 3.53e-03 |
Cardiogenesis | 3.13e-03 | 6.12e-03 |
Cell proliferation | 3.95e-03 | 7.39e-03 |