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Figure 10 | BMC Systems Biology

Figure 10

From: Organizational structure and the periphery of the gene regulatory network in B-cell lymphoma

Figure 10

Hierarchical organization of the K = 25 largest network components of the B-cell C3NET gene regulatory network inferred from the Basso GSE2350 dataset and the DLBCL gene regulatory network inferred from the Salaverria GSE22470 dataset and the Lenz GSE11318 dataset . The numbers of the network components correspond to the leaves of the dendrogram. The GCC corresponds to number ‘1’. A) Clustering of the GO enrichment analysis, category Cellular Component. We show GO terms from the top ranked frequency counts of GO terms for the branches, indicted by the vertical color bars. B) Hierarchical clustering of the structural network components. Left and right: The red part of a dendrogram represents network components with Gene Ontology terms enriched with extracellular and membrane proteins. Green and blue network components are enriched with intracellular proteins.

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