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Table 5 Network similarity analysis for cellular components between the B-cell C3NET gene regulatory network and the Lenz and Salaverria gene regulatory network for 30 from the 58 cellular component subnetworks with the highest correlation coefficient of the betweenness centrality, significant in both comparisons - the columns denote the size (number of genes) of a Gene Ontology term represented in the subnetworks, betw avg the average betweenness for the two comparisons, r avg Spearman’s rank correlation coefficient and p avg the FDR adjusted p-value

From: Organizational structure and the periphery of the gene regulatory network in B-cell lymphoma

GOID Term Size betw avg r avg pval avg (FDR)
GO:0045178 basal part of cell 47 230 0.51 1.83e-03
GO:0035097 histone methyltransferase complex 126 187 0.37 1.98e-02
GO:0031967 organelle envelope 109 212 0.34 4.20e-03
GO:0034361 very-low-density lipoprotein particle 67 183 0.33 2.45e-02
GO:0055037 recycling endosome 82 167 0.31 1.38e-02
GO:0034364 high-density lipoprotein particle 169 172 0.28 2.23e-04
GO:0031461 cullin-RING ubiquitin ligase complex 429 183 0.25 1.17e-04
GO:0030017 sarcomere 325 235 0.24 7.26e-03
GO:0044422 organelle part 350 167 0.21 4.00e-04
GO:0005680 anaphase-promoting complex 295 156 0.20 6.33e-04
GO:0044441 cilium part 654 355 0.20 4.17e-07
GO:0005788 endoplasmic reticulum lumen 368 245 0.20 6.16e-03
GO:0044445 cytosolic part 625 354 0.19 3.01e-06
GO:0005665 DNA-directed RNA polymerase II, core complex 640 264 0.19 5.20e-05
GO:0005789 endoplasmic reticulum membrane 656 247 0.18 8.14e-06
GO:0005903 brush border 2234 414 0.17 2.09e-06
GO:0044432 endoplasmic reticulum part 983 410 0.17 1.43e-07
GO:0005765 lysosomal membrane 1894 338 0.17 2.12e-04
GO:0034703 cation channel complex 923 277 0.17 7.43e-07
GO:0071944 cell periphery 290 198 0.16 1.10e-02
GO:0035085 cilium axoneme 1586 261 0.16 2.62e-10
GO:0005769 early endosome 1585 329 0.16 1.76e-09
GO:0005773 vacuole 1585 285 0.16 2.62e-10
GO:0005768 endosome 1585 324 0.16 1.56e-02
GO:0044309 neuron spine 708 317 0.16 8.22e-05
GO:0044440 endosomal part 3021 287 0.16 1.44e-05
GO:0000313 organellar ribosome 1545 240 0.16 6.90e-04
GO:0005669 transcription factor TFIID complex 1480 308 0.15 5.94e-09
GO:0008305 integrin complex 1609 307 0.15 3.14e-09
GO:0008180 signalosome 1272 245 0.15 1.56e-02