Spice: discovery of phenotype-determining component interplays

BMC Systems Biology

Table 1 H ₂ -related enzymes detected by different methods

Pathway	Enzyme	Enzyme Name	t	SVM-RFE	Spice
Acetate	2.7.2.1	acetate kinase		+	+
	1.3.99.2	butyryl-CoA dehydrogenase		+	+
	2.7.2.7	butyrate kinase	+	+	+
Butyrate	1.1.1.157	3-hydroxybutyryl-CoA dehydrogenase			+
	2.3.1.19	phosphate butyryltransferase	+		+
	2.3.1.9	acetyl-CoA C-acetyl-transferase		+	+
Formate	2.3.1.54	pyruvate formate lyase			+

ISSN: 1752-0509