Table 1 The number of the up and down regulated genes that belong to the curated resistance proteins in INH and ETA
From: Identifying co-targets to fight drug resistance based on a random walk model
Drug resistance | INH | ETA | ||
|---|---|---|---|---|
| Â | Up (+) | Down (-) | Up (+) | Down (-) |
Antibiotic efflux pumps | 7 | 10 | 8 | 9 |
Hypothetical efflux pumps | 2 | 2 | 1 | 3 |
Antibiotic degrading enzymes | 1 | 0 | 1 | 0 |
Target-modifying enzymes | 1 | 0 | 1 | 0 |
SOS and related genes | 5 | 4 | 1 | 8 |
Genes implicated in horizontal gene transfer (HGT) | 1 | 2 | 1 | 2 |
Cytochromes | 15 | 20 | 20 | 15 |