Figure 3

TF concentrations inferred by the model in the synthetic data. The plots in panel (a) (the four plots in the first row) illustrate the estimation of the TF activity using only the first experimental condition. The left plot shows the ground-truth TF activities that generated the observed data. In particular, the coloured solid lines show the three TFs, which were assumed to be known (blue: ANT, red: BEE, green: CAR) and the black dotted line displays the unknown factor UNK. The remaining three plots in panel (a) show the TFs estimated at the training modelling phase. Here, the coloured lines display the estimated means of ANT, BEE and CAR and the shaded areas show 95% credible regions. The plots in panel (b) display the exactly analogous plots with those of (a) with the difference that the second experimental condition was considered instead of the first. The plots in panel (c) illustrate the estimation of TFs by using simultaneously both experimental conditions. The plots in the first row of (c) display the estimates for the first experimental condition, while the plots of the second row display the estimates for the second experimental condition.