Regulator
|
Target
|
Interaction
|
Source
|
Score
|
Reference
|
---|
HapX
|
sreA
|
repression
|
1
|
0.5
|
[29]
|
HapX
|
AFUA_5G10610
|
interaction
|
2
|
0.25
|
[32]
|
HapX
|
mirB
|
activation
|
1,3
|
0.625
|
[32, 51]
|
HapX
|
hemA
|
repression
|
2
|
0.25
|
[32]
|
HapX
|
sdh2
|
repression
|
2
|
0.25
|
[32]
|
input
|
sreA
|
activation
|
2
|
0.25
|
[31]
|
input
|
hapX
|
repression
|
2
|
0.25
|
[32]
|
PacC
|
mirB
|
interaction
|
3
|
0.125
|
[46]
|
PacC
|
ftrA
|
interaction
|
3
|
0.125
|
[46]
|
PacC
|
hem13
|
interaction
|
3
|
0.125
|
[46]
|
SreA
|
sdh2
|
repression
|
2
|
0.25
|
[31]
|
SreA
|
hemA
|
repression
|
2
|
0.25
|
[31]
|
SreA
|
AFUA_5G10610
|
repression
|
2
|
0.25
|
[31]
|
SreA
|
hapX
|
repression
|
1,3
|
0.625
|
[31]
|
SreA
|
mirB
|
repression
|
1
|
0.5
|
[31]
|
SreA
|
ftrA
|
repression
|
1,3
|
0.625
|
[31]
|
SreA
|
sidL
|
repression
|
3
|
0.125
|
[31]
|
SrbA
|
hapX
|
activation
|
1
|
0.5
|
[37]
|
SrbA
|
ftrA
|
activation
|
1
|
0.5
|
[37]
|
SrbA
|
mirB
|
activation
|
1
|
0.5
|
[37]
|
SrbA
|
hem13
|
activation
|
1
|
0.5
|
[37]
|
SreA
|
hem13
|
no interaction
|
1
|
0.5
|
[37]
|
- The table lists regulator-target gene interactions, the type of interaction, the source of prior knowledge, the score used and references. The second part of the table lists additional prior knowledge we exploited in order to refine the model within the second round of modelling. "Input" denotes the fact that a target gene is regulated by the external perturbation (shift from iron replete to iron depleted conditions).