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Figure 2 | BMC Systems Biology

Figure 2

From: Network methods for describing sample relationships in genomic datasets: application to Huntington’s disease

Figure 2

Sample network concepts reveal the profound effect of Huntington’s disease in caudate nucleus. Comparison of standardized sample connectivities (Z.K) and standardized clustering coefficients (Z.C) between control subjects (CTRL) and subjects with Huntington’s disease (HD) in prefrontal cortex (A; n = 9 CTRL and 16 HD), motor cortex (B; n = 16 CTRL and 14 HD), cerebellum (C; n = 23 CTRL and 34 HD), and caudate nucleus (D; n = 31 CTRL and 35 HD). Networks were constructed over all probe sets (n = 18,631) using all samples (CTRL and HD) from each brain region.

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