Figure 2

Network for P53 dataset using GIENA. Network generated using the dysregulated interactions identified by GIENA on the P53 dataset after filtering the significantly differentially expressed genes between cases and controls, and the resulting singletons. The dashed lines indicate that physical interactions between the products of the respective genes are reported in HPRD. The green lines represent competition interactions; purple lines represent dependency interactions; orange lines represent redundancy interactions. The blue lines indicate that these interactions were detected by multiple interaction profiles. Note that there is no cooperation interaction presented in this network, because no unique pathway is detected by cooperation profile.