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Table 2 Q-values of pathways detected by GIENA for the pancreatic cancer dataset

From: Gene interaction enrichment and network analysis to identify dysregulated pathways and their interactions in complex diseases

Pathway Cooperation Competition Redundancy Dependency GSA
Glycosphingolipid biosynthesis 0.018 0.002 0.004 0.027 0.064
Classic complement activation 0.047 0.003 0.040 0.027 0.052
Classic 0.047 0.003 0.034 0.027 0.064
Classic & alternative complement 0.047 0.004 0.039 0.026 0.052
ACE2 0.047 0.004 0.027 0.026 0.064
Bisphenol A degradation 0.049 0.009 0.048 0.027 0.064
Lysine degradation 0.037 0.009 0.040 0.028 0.061
Renin-angiotensin system 0.047 0.009 0.035 0.027 0.052
Glycosphingolipid biosynthesis (neo-lactoseries) 0.018 0.026 0.004 0.027 0.064
  1. q-value < 0.01 is considered as significant, and highlighted in bold. Note none of pathways has significant q-value using GSA.