Skip to main content

Table 3 Features of three bistable switches obtained with the basal motif

From: A simple theoretical framework for understanding heterogeneous differentiation of CD4+ T cells

Bistable switch Phenotypic transition controlled by the switch Underlying positive feedback loops Type of related heterogeneous differentiation
Differentiation Naïve XSP or YSP Auto-activation NA
Reprogramming XSP YSP Created by mutual inhibition and enhanced by auto-activation Type 1
Co-expression XSP or YSP DP Auto-activation Type 2