Figure 7

The onset of action potential oscillations is altered by calcium transients in eleven adjacent spines, with an 800 ms current injection and a different timing sequence between PF and CF stimuli. a, Membrane potential oscillations at the soma (top panel) and the spine (bottom panel) in response to a 800 ms depolarizing current injection at the soma (no calcium influx or release). b, Membrane potential oscillations at the soma (top panel) and at the spine (bottom panel) in response to a depolarizing current injection at the soma superimposed with calcium release only (160 ms after the start of the current injection). c, Membrane potential oscillations at the soma in response to a depolarizing current injection at the soma superimposed with calcium influx only (220 ms after the start of the current injection). d, Membrane potential oscillations at the soma in response to a depolarizing current injection at the soma superimposed with both calcium release and influx. e, Corresponding calcium transients at the spine. f, Corresponding changes in BK channel conductance.