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Table 4 Constraints for metabolite uptake rates used for model simulation, and the comparison of the predicted growth rate by the in silico model and observed growth rate from the experiments in each growth condition

From: i AK692: A genome-scale metabolic model of Spirulina platensis C1

Growth conditions Constraints of consumed metabolites (mmol/mmol dry cell/h) Maximal specific growth rate (1/h)
  Bicarbonate Phosphate Nitrate* Sulfate* Glucose** In silico In vivo
Autotrophic 0.20 0-0.0056 0-0.040 0-0.0014 0 0.0257 0.0255
Heterotrophic 0 0-0.0056 0-0.040 0-0.0014 0.017 0 0
Mixotrophic 0.20 0-0.0056 0-0.040 0-0.0014 0.017 0.0334 0.0262
  1. * data from ref. 38.
  2. ** data from ref. 39.