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Table 4 Constraints for metabolite uptake rates used for model simulation, and the comparison of the predicted growth rate by the in silico model and observed growth rate from the experiments in each growth condition

From: i AK692: A genome-scale metabolic model of Spirulina platensis C1

Growth conditions

Constraints of consumed metabolites (mmol/mmol dry cell/h)

Maximal specific growth rate (1/h)

 

Bicarbonate

Phosphate

Nitrate*

Sulfate*

Glucose**

In silico

In vivo

Autotrophic

0.20

0-0.0056

0-0.040

0-0.0014

0

0.0257

0.0255

Heterotrophic

0

0-0.0056

0-0.040

0-0.0014

0.017

0

0

Mixotrophic

0.20

0-0.0056

0-0.040

0-0.0014

0.017

0.0334

0.0262

  1. * data from ref. 38.
  2. ** data from ref. 39.