Table 2 Reactions of the transport model

(R1)

$\varnothing \to {\mu }_{1}V$

Creation of cargo

Cell body

(R2–R5)

$V\stackrel{{\sigma }_b}{\underset{{\sigma }_d}{\rightleftharpoons }}{V}^{k,d}$

Binding of V to microtubule

All domains

(R6,R7)

$V^k\stackrel{{\sigma }_{\mathrm{kd}}}{\underset{{\sigma }_{\mathrm{dk}}}{\rightleftharpoons }}{V}^d$

Reversal of direction

Microtubule

(R8)

$V\to {\mu }_2\varnothing$

Degradation of V

All domains